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Changes of urine kidney injury molecule-1 and N-acetyl-ß-D-glocosaminidase levels in patients with chronic heart failure and its relationship with prognosis.

Changes of urine kidney injury molecule-1 and N-acetyl-ß-D-glocosaminidase levels in patients with chronic heart failure and its relationship with prognosis.

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000040217
Enrollment
Unknown
Registered
2020-11-25
Start date
2020-11-30
Completion date
Unknown
Last updated
2021-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic heart failure

Interventions

Heart failure group:Conventional medications for heart failure
Control group:Blank control

Sponsors

Hanzhong Central Hospital, Shaanxi province,China.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Hospitalized patients who had chronic heart failure with NYHA class III or IV; 2. The patient has symptoms and signs of chronic heart failure; 3. NT-proBNP>125 pg/mL; 4. Aged over 18 years old; 5. Patients who agree and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients who had a history of chronic kidney disease or acute kidney disease, diabetes, hypothyroidism, hyperthyroidism, acute or chronic infection, chronic liver, pregnancy,cancer,and high alcohol intake were excluded from the the study; 2. Patients combined with severe primary or secondary diseases of other systems; 3. Patients have been using biological agents within 3 months; 4. Patients who are unsuitable for this clinical trial considered by researchers; 5. Patients who with poor compliance were excluded from the study.

Design outcomes

Primary

MeasureTime frame
KIM-1;

Secondary

MeasureTime frame
Beta 2-MG;Ucr;NAG;

Countries

China

Contacts

Public ContactDang Qun

Hanzhong Central Hospital

362542802@qq.com+86 13892656865

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026