Chronic ankle instability
Conditions
Interventions
Group 1:dextrose 15%
Sponsors
Investigator sponsored trial
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: The inclusion criteria include age >=18 years old, with a diagnosis of CAI, defined as having at least 1 significant ankle sprain, and at least 2 episodes of giving way in the 6 months prior to study enrollment ,and a Cumberland Ankle Instability Tool (CAIT) score 20%.
Exclusion criteria
Exclusion criteria: The exclusion criteria include acute ankle sprain <=6 months; complete tear of ATFL confirmed by USG or MRI; a history of previous surgeries to the musculoskeletal structures (ie, bones, joint structures, nerves) in either lower extremity; acute injury to musculoskeletal structures of other joints of the lower extremity in the previous 3 months that impacted joint integrity and function (ie, sprains, fractures), resulting in at least 1 interrupted day of desired physical activity; a history of a fracture in either lower extremity requiring realignment; high ankle sprain, generalized ligament laxity; pregnancy; on anti-coagulant therapy; prior ATFL or ankle injections within 3 months; inflammatory or post-infectious ankle arthritis, such as clinically diagnosed rheumatoid arthritis, gouty arthritis, psoriatic arthritis and septic arthritis; history of corn allergy and co-morbidity or lifestyle preventing participation in the study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Cumberland Ankle Instability Tool (CAIT); | — |
Secondary
| Measure | Time frame |
|---|---|
| Total number of re-sprains;Star Excursion Balance Test (SEBT);EuroQoul-5 dimensions questionnaire (EQ-5D-5L);Utilization of health services;Assessment the success of blinding;Chinese version of Foot and Ankle Ability Measure; | — |
Countries
China
Contacts
Public ContactProf. Regina Wing-Shan SIT
The Chinese University of Hong Kong
Outcome results
None listed