Branch retinal vein occlusion
Conditions
Interventions
Sponsors
Eye Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Meet the following Western medicine diagnostic criteria for branch retinal vein occlusion and TCM diagnostic criteria, and the course of disease is more than 2 weeks; 2. Aged between 40 and 70 years old; 3. Subjects who fully understand the project and voluntarily sign the informed consent; Western medicine diagnostic criteria; (1) Sudden vision loss or black shadows in front of the eyes; (2) Dilated and tortuous retinal veins in the fundus, hemorrhage and edema on the surface of the affected veins; (3) Fundus fluorescein angiography: retinal vein filling time is delayed, capillary leakage, and no perfusion area is visible; (4) OCT examination showed macular edema, and the thickness of the fovea was more than 300um. TCM diagnostic criteria: Main symptoms: (1) decreased vision; (2) retinal hemorrhage, edema, exudation, and venous filling. Secondary symptoms: (1) body obesity, less gas and lazy speech; (2) dizziness, fatigue, fatigue; (3) chest tightness, discomfort, swelling full of swelling; (4) greasy tongue coating or tongue petechiae; (5) stringy or slippery pulse. With 2 primary syndromes and 3 secondary syndromes (necessary for tongue picture), the syndrome can be differentiated into this syndrome type.
Exclusion criteria
Exclusion criteria: 1. Patients with late central vision loss; 2. Patients with other fundus diseases; 3. Pregnant or lactating women; 4. Patients with severe cardiovascular and cerebrovascular diseases or severely impaired liver and kidney function and systemic failure; 5. Patients who are participating in clinical trials of other drugs or who have used similar Chinese medicines and other treatments; 6. Subjects who are not willing to participate in clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| vision acuity;Optical coherence tomography angiography (OCTA): central macular thickness (CMT), superficial and deep retina capillary density, non-perfusion area (NPA), foveal avascular area (FAZ).; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fundus fluorescein angiography (FFA): Record the retinal circulation time, blockage, area of non-perfusion area, and whether there is neovascularization and vascular leakage.; | — |
Countries
China
Contacts
Public ContactHao Xiaofeng
Eye Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed