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The influence of weight on prophylactic norepinephrine infusions for preventing spinal anesthesia-induced hypotension during cesarean delivery

The influence of weight on prophylactic norepinephrine infusions for preventing spinal anesthesia-induced hypotension during cesarean delivery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040157
Enrollment
Unknown
Registered
2020-11-22
Start date
2020-12-01
Completion date
Unknown
Last updated
2021-01-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal anesthesia-induced hypotension during cesarean delivery

Interventions

low weight group(body weight 50-70 kg):Each patient received a prophylactic infusion of 5µg/ml norepinephrine delivered using a syringe pump and started at the time of intrathecal injection.For the fi
high weight group(body weight 70-90 kg):Each patient received a prophylactic infusion of 5µg/ml norepinephrine delivered using a syringe pump and started at the time of intrathecal injection.For the f

Sponsors

Obstetrics and Genecology Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) physical status I/II and full-term women with singleton pregnancy scheduled for elective cesarean delivery under regional anesthesia

Exclusion criteria

Exclusion criteria: Height 170 cm, allergy to norepinephrine, preexisting or pregnancy-induced hypertension, cardiovascular or cerebrovascular disease, diabetes mellitus, fetal abnormalities, obstetric complication (ruptured membranes, placenta praevia, placental abruption),and any contraindication to spinal or epidural anaesthesia.

Design outcomes

Primary

MeasureTime frame
the incidence of hypotension;

Secondary

MeasureTime frame
the incidence of hypertension;the incidence of bradycardia;the incidence of nausea;the incidence of vomiting;the incidence of shivering;Apgar scores 1 and 5 min after delivery;measurement of umbilical arterial blood gases;

Countries

China

Contacts

Public ContactShaoqiang Huang

Obstetrics and Genecology Hospital of Fudan University

timrobbins71@163.com+86 13918210787

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026