Postoperative recovery and analgesia
Conditions
Interventions
s group:15min before induction of anesthesia, intravenous pump injection of dexmedetomidine 0.5ug/kg/h, intraoperative dexmedetomidine 0.2ug/kg/h continuous infusion until the start of suture
c group:15min before induction of anesthesia, intravenous pump injection of equal dose of normal saline,intraoperative continuous infusion same volume of normal salineuntil the start of suture
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients between 65 and 80 years old; ASA I-III; 2. Patients who scheduled elective laparotomy for radical gastric cancer; 3. No psychiatric disease, chronic pain disease, long-term history of opioid use; 4. Patients who can understand the use of QOR-15 scale; 5. The subjects who will sign informed consent and agree to be included in the study.
Exclusion criteria
Exclusion criteria: 1. Patients who are contraindicated with dexmedetomidine (allergies, severe bradycardia, atrioventricular block, cardiac insufficiency, etc.); 2. Severe anemia before operation (Hb<70g/L); 3. Other reasons why researchers think necessary to exclude.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative recovery quality Postoperative recovery quality score;VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| HR, MAP;Intraoperative opioid use;analgesics consumption in 24 hours after surgery;Incidence of postoperative nausea, vomiting, or delirium; | — |
Countries
China
Contacts
Public ContactLiu Jin
West China Hospital, Sichuan University
Outcome results
None listed