Elderly patients
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) The patients aged 65 to 80 years old; patients who planned to undergo endotracheal intubation; ASA score of grade I or II or grade III; 2) BMI 18 to 30kg/m2; 3) They clearly understood and voluntarily participated in the study, and their informed consent was signed by themselves.
Exclusion criteria
Exclusion criteria: 1) Patients who refuse to participate or who are not suitable to participate in the trial; 2) Those who are sensitive to esmamine and related drugs; 3) In the past, there were contraindications for ketamine use, such as severe refractory hypertension, pulmonary heart disease, hyperthyroidism, epilepsy, increased intraocular pressure, intracranial space occupying lesions, and history of cerebrovascular accidents; 4) There was a history of alcoholism or taking psychotropic drugs or analgesics within 24 hours before operation; 5) Epileptic seizures; 6) Use drugs that affect the central nervous system; 7) He had a history of severe depression, mental and neurological diseases in the past. 8) The researchers believe that patients should not participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy evaluation; | — |
Countries
China
Contacts
Tianjin Fourth Central Hospital