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Effect of primary prevention of esophageal varices on survival and prognosis of primary hepatocellular carcinoma

Effect of primary prevention of esophageal varices on survival and prognosis of primary hepatocellular carcinoma

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040120
Enrollment
Unknown
Registered
2020-11-21
Start date
2021-01-01
Completion date
Unknown
Last updated
2021-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Hepatocellular Carcinoma

Interventions

Varicose ligation group:Varicose vein ligation
Control group:No ligation

Sponsors

The Second People's Hospital of Yibin, Sichuan Province
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) for newly diagnosed patients with liver cancer, the diagnostic criteria of liver cancer meet the diagnostic criteria of European Association of Hepatology: at least two of dynamic contrast-enhanced MRI, dynamic contrast-enhanced CT and contrast-enhanced ultrasound have typical characteristics of liver cancer or AFP >=400ug/ml, and one of the above imaging examinations has typical characteristics of liver cancer; (2) 18 ~ 80 years old; (3) No other tumors affected the prognosis; (4) No previous history of esophageal vein ligation; (5) Newly diagnosed liver cancer patients are willing to accept endoscopic screening within 3 months.

Exclusion criteria

Exclusion criteria: (1) patients with severe heart, brain and lung diseases who cannot be screened by endoscopy; (2) Bleeding from esophageal or gastric varices in the past; (3) Liver cancer patients who have received liver transplantation before.

Design outcomes

Primary

MeasureTime frame
Overall survival rate;Bleeding rate;

Countries

China

Contacts

Public ContactLuo Yongping

Yibin Second People's Hospital

1656449931@qq.com+86 18090968857

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026