Transplantation of acellularized dermis matrix plus fully covered metal stent to prevent stricture after circumferential endoscopic submucosal dissection of early esophageal cancer (with video)

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000040115

Enrollment

Unknown

Registered

2020-11-21

Start date

2019-06-01

Completion date

Unknown

Last updated

2021-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal stricture after circumferential endoscopic submucosal dissection of early esophageal cancer

Interventions

Case series:acellularized dermis matrix

Eligibility

Sex/Gender

All

Age

30 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients with EEC expected to result in a above 3/4-circumference post-ESD artificial ulcer; 2. Patients who can tolerate endoscopic treatment under general anesthesia; 3. Patients who agreed to participate in the clinical trial and signed informed consent for surgery.

Exclusion criteria

Exclusion criteria: 1. Patients with eating disorders and absorption disorders caused by other reasons; 2. Patients with diabetes, autoimmune diseases, and a recent history of taking drugs such as hormones and immunosuppressant; 3. Patients with severe cardiovascular and cerebrovascular diseases, severe hepatic and renal insufficiency, and a history of severe chronic pulmonary disease; 4. Patients with acute or chronic infections.

Design outcomes

Primary

Measure	Time frame
with or without stricture occurrence;adverse events;tumor invasion depth;The number of ADM patches;Epithelialization time;	—

Countries

China

Contacts

Public ContactXingli Mao

Taizhou Hospital of Zhejiang Province

maoxl@enzemed.com+86 13566866269

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026