Type 2 dibetes combined with hypertension
Conditions
Interventions
1:Empagliflozin 10mg/d
2:Routine treatment group
Sponsors
The Second Affillicated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 to 70 years old; 2. For patients with poor glycemic control using one or more hypoglycemic drugs(Excluding in the use of SGLT2 inhibitors or GLP1 receptor agonists); 3. HbAlc 7.5~11%, FBS<=15mmol/l; BMI 18~35kg/m2; 4. Combined with hypertension; 5. Patients with good blood pressure control; 6. Signed the inform consent.
Exclusion criteria
Exclusion criteria: 1. With cardiac dysfunction,hepatic and renal dysfunction; 2. Patients already in the use of SGLT2 inhibitors or GLP1 receptor agonists; 3. Urinary or reproductive tract infections; 4. Patients with tumors and chronic infections,psychopaths,hematological system and immune system diseases; 5. Pregancy and lactating women; 6. Patients with acute or chronic sever diabetic complications or concomitant diseases,such as storke,acute coronary syndrome and so on; 7. Patients with severe hearet diseases,poor blood pressure control and previous heart surgery; 8. Participants in other clinical trails during the same period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure variability;left ventricular mass index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glycosylated hemoglobin;Fast blood glucouse;2-hour post-meal blood glucose;blood lipid;urine microalbuminuria/creatinine;hepatic function;renal function; | — |
Countries
China
Contacts
Public ContactZhong Xing
The Second Affillicated Hospital of Anhui Medical University
Outcome results
None listed