Lung cancer
Conditions
Interventions
Sponsors
Department of Radiotherapy, Cancer Center, Shandong Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years old; 2. Patients with EGFR-positive advanced non-squamous non-small cell lung cancer, including: first-line treatment for patients with recurrence or metastasis (patients who relapse within 6 months after completion of adjuvant treatment are allowed to be included in the group); Note: Adjuvant therapy allows the use of chemotherapy or EGFR-TKIs. Patients who can continue to use EGFR-TKIs after the first-line EGFR-TKIs treatment progresses; 3. Volunteer to join this study and sign an informed consent form; 4. The researcher thinks it can benefit.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Patients with contraindications to apatinib or EGFR-TKIs (eg: active bleeding, ulcers, intestinal perforation, intestinal obstruction, drug-uncontrollable hypertension, grade III-IV cardiac insufficiency, within 30 days after major surgery , Severe liver and kidney dysfunction, etc.); 3. Doctors consider not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PFS; | — |
Countries
China
Contacts
Public ContactYang Zhe
Department of Radiotherapy, Cancer Center, Shandong Provincial Hospital
Outcome results
None listed