FindTrial
Sign In

Comparison of continued infusion of methoxamine and phenylephrine to prevent and treat combined spinal epidural anesthesia induced hypotension in cesarean deliveryies

Comparison of continued infusion of methoxamine and phenylephrine to prevent and treat combined spinal epidural anesthesia induced hypotension in cesarean deliveries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040088
Enrollment
Unknown
Registered
2020-11-20
Start date
2020-11-14
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypotension

Interventions

Phenylephrine group:phenylephrine infusion at 0.5ug/kg/min
methoxamine group:methoxamine infusion at 0.5ug/kg/min

Sponsors

Department of Anesthesiology,West China Second University Hospital,Key Laboratory of Birth Defects and Related Diseases of Women and Children,Sichuan University,Ministry of Education
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Parturients, American Society of Anesthesiologists physical status (ASA <=2), singleton pregnancy, scheduled for elective cesarean delivery, undertaken combined spinal-epidural anesthesia.

Exclusion criteria

Exclusion criteria: Body mass index >30kg/m2, height 170 cm, anemia (hemoglobin<9 g/dl ), known cardiovascular or cerebrovascular disease, pre-existing or pregnancy-induced hypertension, diabetes mellitus, fetal abnormality, monoamine oxidase inhibitors undertaken or contraindication to spinal anesthesia.

Design outcomes

Primary

MeasureTime frame
Blood pressure;—

Countries

China

Contacts

Public ContactXuemei Lin

West China Second University Hospital, Sichuan University

xuemeilin__scu@163.com+86 18180609220

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026