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Rabeprazole with amoxicillin or furazolidone dual therapy for helicobacter pylori infection: a single center, prospective, randomized, open-label controlled trial

Rabeprazole with amoxicillin or furazolidone dual therapy for helicobacter pylori infection: a single center, prospective, randomized, open-label controlled trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040051
Enrollment
Unknown
Registered
2020-11-19
Start date
2020-04-01
Completion date
Unknown
Last updated
2021-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

helicobacter pylori infection

Interventions

group A:bismuth quadruple therapy
group B:Amoxicillin dual therapy
group C:Furazolidone dual therapy

Sponsors

Henan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients who were diagnosed as HP positive by 13 C-urea breath test, the serum antibody test, gastroscope need to eradicate H. pylori; 2. Adult patients aged between 18 -70 years; 3. Informed and agreed to sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Use of PPI, bismuth, antibiotics one month before initiating study treatment; 2. Previous treatment history of helicobacter pylori; 3. Previous surgical history of upper gastrointestinal diseases; 4. Pregnant and breastfeeding patients; 5. Presence of diseases, such as mental illness, severe respiratory, liver or kidney disease, malignant tumors and other diseases before entering hospital; 6. Alcohol abuse or other conditions of increasing adverse reaction risks; 7. Patients with less compliance.8.Allergy to related medications or severe adverse reactions; 8. Allergy to related medications or severe adverse reactions.

Design outcomes

Primary

MeasureTime frame
eradication rate;

Secondary

MeasureTime frame
adverse reaction;cost-efficacy ratio;Compliance;

Countries

China

Contacts

Public ContactSong-Ze Ding

Henan Provincial People's Hospital

sykyxmbgs@163.com+86 18538297582

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026