general anesthesia
Conditions
Interventions
THRIVE group:THRIVE
Sponsors
The Second Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. American society of anesthesiologists (ASA) class I - III physical situation; 2. Aged 18 to 65 years old; 3. Patients undergoing elective surgery under general anesthesia; 4. Patients who need to enter the PACU for tracheotracheal extubation.
Exclusion criteria
Exclusion criteria: 1. Refuse to participate in the study; 2. Obese patients (BMI>30kg/m2); 3. Preoperative known or estimated difficult airway; 4. Patients with a history of severe chronic obstructive pulmonary disease (COPD severity grade III or IV), severe or uncontrolled bronchial asthma, pulmonary infection, bronchiectasis, thoracic deformity, and intrathoracic diseases (such as mediastinal and thoracic tumors); 5. Patients with acute coronary syndrome, persistent ventricular tachyarrhythmia, NYHA grade III or IV severe heart disease; 6. Patients with cirrhosis and ascites with Child grade B or C; 7. Chronic renal failure patients with CKD stage 4 or 5 requiring dialysis; 8. Patients with severe neuromuscular diseases such as myasthenia gravis, progressive muscular dystrophy and periodic paralysis; 9. Patients undergoing tracheal intubation under airway surgery and periairway surgery (such as strut laryngoscope, thyroid surgery, etc.); 10. Patients with high risk of aspiration in emergency, satiety and reflux; 11. Atropine is forbidden in patients with glaucoma, prostatic hypertrophy, atropine allergy, etc.; 12. People with hearing, intelligence, communication and cognitive impairment; 13. Patients who could not monitor EIT due to the incision location.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of respiratory depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure,BP;Heart rate,HR;ST;cardiac output,CO;systemic vascular resistance, SVR;stroke volume, SV;Stroke Volume VariationStroke volume variation;Cerebral re-gional oxygen saturation, rSO2;Spectral edge frequency,SEF;patient state index,PSI;Train-of-Four Stimulation,TOF;respiratory rate,RR;arterial partial pressure of oxygen,PaO2;arterial partial pressure of carbondioxide,PaCO2;arterial oxygen saturation,SaO2;bicarbonate ion,HCO3-;Lactic acid,Lac;end-expiratory lung impedance, ?EEL1,?EEL2,?EEL3,?EEL4;region of interests ventilation,ROI1,ROI2,ROI3,ROI4;restlessness;Choking cough;The tongue after falling;Sore throat;hearing;Breathless time;White blood cell count;Postoperative recovery quality score;Pulse oxygen saturation,SPO2; | — |
Countries
China
Contacts
Public ContactHe Huang
Department of Anesthesiology, The Second Affiliated Hospital of Chongqing Medical University
Outcome results
None listed