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Comparison of ultrasound-guided thoracoabdominal nerves block through perichondrial approach and oblique subcostal transversus abdominis plane block in laparoscopic cholecystectomy: a prospective, randomized study

Comparison of ultrasound-guided thoracoabdominal nerves block through perichondrial approach and oblique subcostal transversus abdominis plane block in laparoscopic cholecystectomy: a prospective, randomized study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040046
Enrollment
Unknown
Registered
2020-11-19
Start date
2020-12-01
Completion date
Unknown
Last updated
2022-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laparoscopic cholecystectomy

Interventions

Perichondral approach for blockage of thoracoabdominal nerves group:Perichondral approach for blockage of thoracoabdominal nerves
Oblique subcostal transversus abdominis plane block group:Oblique subcostal transversus abdominis plane block

Sponsors

Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 ~ 60 years; 2. ASA grade I ~ II; 3. To perform elective laparoscopic cholecystectomy.

Exclusion criteria

Exclusion criteria: 1.Contraindications for abdominal nerve block, including abnormal coagulation function, puncture site infection, allergy to local anesthetics; 2.Chronic pain, neuropathic pain, long-term use of analgesics or other psychotropic drugs; 3.History of abdominal surgery; 4.Morbid obesity (BMI >= 35kg/m2); 5.History of motion sickness or postoperative nausea and vomiting; 6.A digestive ulcer or bronchial asthma; 7.Unable to cooperate with researchers for any reason.

Design outcomes

Primary

MeasureTime frame
Sufentanil dosage 24h after surgery;

Secondary

MeasureTime frame
sufentanil consumption at 12 h intervals (0-12 h, and 12-24 h) after surgery ;The pain scores both at rest and during coughing were assessed with NRS at 30th minute, 1st, 2 nd, 6 th, 12 th and 24?th hours postoperatively;The number of people required remedial analgesia;Time of the first opioid requirement;Consumption of remifentanil and propofol intraoperatively ;Time of removing the endotracheal tube postoperatively; The incidence of complications (PONV, infection, bleeding and subcutaneous hematoma) ;

Countries

China

Contacts

Public ContactXu Yahui

Affiliated Hospital of Xuzhou Medical University

1371011721@qq.com+86 18755126308

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026