Acute lung injury after cardiopulmonary bypass after cardiac surgery
Conditions
Interventions
Injury group A:5ml venous blood was extracted from patients at three time points before anesthesia (T1), before the start of extracorporeal circulation after anesthesia (T2), and after the end of extr
Control group C:5ml venous blood was extracted from patients at three time points before anesthesia (T1), before the start of extracorporeal circulation after anesthesia (T2), and after the end of ext
Sponsors
Department of Anesthesiology, Shandong provincial Qianfoshan Hospital, the First Hospital Affiliated with Shandong First Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Type of surgery: Adult heart valve replacement surgery, preoperative control of cardiac function within the compensatory range, and grade I-III cardiac function according to NYHA classification criteria; 2. Extracorporeal circulation was performed during the operation; 3. Aged >=18 years.
Exclusion criteria
Exclusion criteria: 1. Patients with preoperative heart failure and NYHA assessment of cardiac function at grade IV, which cannot be corrected; 2. Patients with preoperative pulmonary hypertension; 3. Patients with preoperative pulmonary function abnormalities, including pneumonia, pulmonary fibrosis, pulmonary edema, etc.; 4. Unplanned secondary surgery; 5. Failure of operation, no improvement of cardiac function after operation; 6. The patient refused to do the study; 7. Patients with abnormal mental state and unable to cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Regulatory T cells; | — |
Countries
China
Contacts
Public ContactYuelan Wang
Department of Anesthesiology, Shandong provincial Qianfoshan Hospital, the First Hospital Affiliated with Shandong First Medical University
Outcome results
None listed