Neurocognitive impairment
Conditions
Interventions
Control group:Placebo
Sponsors
Shanghai Mental Health Center
Eligibility
Sex/Gender
All
Age
50 Years to 90 Years
Inclusion criteria
Inclusion criteria: Entry criteria 1. Meet the MMSE scale: MMSE 11 to 26 points (subjects with elementary school education MMSE 11 to 22 points); 2. CDR score 0.5-2.0; 3. Comply with the diagnostic criteria of syndromes of deficiency of both heart and spleen in TCM; 4. Geriatric Depression Scale (GDS) <=10 points; 5. Those who have a clear consciousness, volunteer to participate, cooperate with various examinations and treatments, and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Those who do not meet the above standards or have incomplete data or who have severe neurological impairment (severe hemiplegia, various aphasia, and visual and hearing impairment) or who are unwilling to accept research measures; 2. Those who have other diseases that can cause dysfunction or severe heart, liver, kidney disease or severe mental symptoms; 3. Patients with certain diseases or bad habits that can interfere with the evaluation of cognitive function, including those who add alcohol, drugs, or abuse other psychotropic drugs; 4. Patients suffering from severe indigestion, or gastrointestinal obstruction or other gastrointestinal diseases that affect drug absorption; 5. Those who have taken sedatives, hypnotics, antipsychotics, antidepressants, and central stimulants for a long time, and cannot stop the drug for 1 month before the study; 6. Those who have taken related or antagonistic drugs in the past 1 month, making it difficult to judge the efficacy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Psychobehavioral symptoms; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep condition;TCM Syndrome Score; | — |
Countries
China
Contacts
Public ContactXia Li
Shanghai Mental Health Center
Outcome results
None listed