depression
Conditions
Interventions
treatment group:accelerate bilateral TBS
waiting group:accelerate bilateral TBS
Sponsors
Shenzhen Kangning Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. All the included patients met the diagnostic criteria for depressive episode in ICD-10, and it was the first episode; 2. A definite diagnosis of depressive episode by an attending psychiatrist and an associate chief psychiatrist; 3. The answer for the fourth or fifth item of Beck Suicidal Ideation Scale- Chinese version is "weak" or "moderate to strong"; 4. Age 18-65 years old, men and women are not limited, right-handed; 5. There were no contraindications to TMS in EEG; 6. No regular use of antidepressants, mood stabilizers, benzodiazepines, antipsychotics, rTMS or MECT, and no systematic psychotherapy within 2 weeks prior to inclusion; 7. Willing and informed consent to participate in this study.
Exclusion criteria
Exclusion criteria: 1.Exclude history of serious physical diseases, organic brain diseases and mental disorders caused by thyroid diseases or other physical diseases; 2.Exclude depression or psychogenic depression caused by other psychoactive substances or non-dependent substances, comorbidity compulsive disorder/schizophrenia/comorbidity borderline personality disorder/substance abuse or addiction, and history of hypomania/manic episodes; 3.Exclude patients with poor communication comprehension or cognitive impairment who cannot complete the psychological assessment, or who are difficult to complete the psychological assessment due to other reasons; 4.Patients with intracranial metal materials, pacemakers and stents, cataract lens replacement surgery, epilepsy risk, family history of epilepsy, pregnant and lactating women were excluded; 5.Excluding a history of suicide attempt, severe non-suicidal self-injuriou behavior, suicidal behavior in the waiting period, or unsuitability for further participation in this study due to illness or other reasons during the waiting period; 6.Those who have no intention to participate in this study and quit before rTMS are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Beck Scale for Suicide Ideation-Chinese Version;Hamilton's Depression Scale -24; | — |
Countries
China
Contacts
Public ContactLingyun Zeng
Shenzhen Kangning Hospital
Outcome results
None listed