oral leukoplakia
Conditions
Interventions
non canceration group:Nil
leukoplakia canceration group:Nil
Sponsors
Shanghai Jiao Tong University, School of Medicine, Shanghai Ninth People's Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Over 20 years old (including 20 years old), under 80 years old (including 80 years old), regardless of gender; (2) The white plaque was histopathologically confirmed as oral mucosal white plaque; (3) No other induced differentiation treatments (including oral/ external use of retinoic acid) before going to our hospital. (4) If the pregnancy test of female subjects of childbearing age is negative, they shall agree to use effective contraceptive measures to ensure that they will not become pregnant during the test and within 3 months after the cessation of treatment.
Exclusion criteria
Exclusion criteria: (1) Definite distant metastasis or occurrence of other malignant tumors; (2) persons suffering from mental illness and unable to cooperate with the treatment; (3) The function of important organs is impaired and life is in danger; (4) Patients with abnormal coagulation function and bleeding tendency; (5) Pregnant or lactating women; (6) Participated in other clinical trials within the previous 30 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EZH2 protein expression; | — |
Countries
China
Contacts
Public ContactHaiwen Zhou
Shanghai Jiao Tong University, School of Medicine, Shanghai Ninth People's Hospital
Outcome results
None listed