Clinical study of sodium bicarbonated Ringer's solution on fluid resuscitation of patients with hemorrhagic shock

Clinical study of sodium bicarbonated Ringer's solution on lactate level targeted resuscitation strategy in shock patients

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000039951

Enrollment

Unknown

Registered

2020-11-15

Start date

2020-11-09

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemorrhagic shock

Interventions

sodium bicarbonate Ringer's solution group:patients receive sodium bicarbonate Ringer's solution for resuscitation

control group:5% sodium bicarbonate + normal saline + compound sodium chloride

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-60 years; 2. Patients with hemorrhagic shock; 3. Patients with arterial blood lac >= 4 mmol / L.

Exclusion criteria

Exclusion criteria: 1. Patients with severe hepatic insufficiency (child grade C); 2. Patients with severe renal failure (creatinine > 400 µ mol / L, urea nitrogen > 27 mmol / L); 3. Patients with severe coagulation dysfunction; 4. Patients with hypermagnesemia; 5. Patients with hypothyroidism; 6. Patients who used various acids and bases within 6 hours before admission; 7. Patients with malignant tumor.

Design outcomes

Primary

Measure	Time frame
Blood gas analysis;28-day mortality;	—

Secondary

Measure	Time frame
6h lactic acid clearance rate;Central venous pressure;Mean arterial pressure;	—

Countries

China

Contacts

Public ContactYu Liqin

Wuwei People's Hospital

yuliqin6639@sina.com+86 13809356806

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026