Effect of intraoperative application of esketamine on perioperative analgesia of lumbar fusion

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000039950

Enrollment

Unknown

Registered

2020-11-15

Start date

2020-12-01

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain

Interventions

experimental group:Esketamine

control group:normal saline

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Subjects aged from 18 to 85, regardless of gender; 2. Patients scheduled for lumbar fusion under general anesthesia; 3. Subjects with physical condition of American Society of anesthesiologists (ASA) grade I-III; 4. The subjects who agreed to participate in the clinical study and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with severe heart or lung diseases; 2. Patients with severe liver or renal insufficiency; 3. Patients who are allergic to the drugs to be used; 4. Subjects who abuse alcohol or analgesic, sedative or antidepressant drugs; 5. In patients with uncontrollable hypertension, intraocular pressure increases; 6. Pregnant subjects; 7. Subjects with mental illness or unconsciousness were unable to understand the relevant scales or use the patient-controlled analgesia device.

Design outcomes

Primary

Measure	Time frame
Types and dosages of opioids used;Pain score;	—

Countries

China

Contacts

Public ContactGe Jianyun

The Second Affiliated Hospital of Nantong University

34104645@qq.com+86 15962878208

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026