Postoperative Cognitive Dysfunction
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who meet the indications of unilateral hip replacement and accept elective surgery; 2. Patients without cognitive impairment were screened by MMSE and MOCA before operation; 3. Subjects of ASA grade I - III; 4. Subjects aged 65-85 years.
Exclusion criteria
Exclusion criteria: 1. Subjects with previous history of hip replacement; 2. Patients who underwent emergency operation again due to postoperative bleeding and other surgical factors; 3. Patients with a history of nervous system diseases, such as stroke, etc; 4. Subjects with visual and auditory impairment and middle ear disease; 5. Subjects with mental or emotional diseases who can not cooperate; 6. Patients with contraindication of butorphanol tartrate; 7. Pregnant or lactating subjects; 8. Patients refuse to participate or are participating in other intervention studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMSE score; | — |
Countries
China
Contacts
Department of Anesthesiology, Affilicated Hospital of Xuzhou Medical University