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Effect of Butorphanol on early postoperative cognitive impairment in elderly patients undergoing hip arthroplasty

Effect of Butorphanol on early postoperative cognitive impairment in elderly patients undergoing hip arthroplasty

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039937
Enrollment
Unknown
Registered
2020-11-14
Start date
2021-11-20
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Cognitive Dysfunction

Interventions

Sponsors

Affilicated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients who meet the indications of unilateral hip replacement and accept elective surgery; 2. Patients without cognitive impairment were screened by MMSE and MOCA before operation; 3. Subjects of ASA grade I - III; 4. Subjects aged 65-85 years.

Exclusion criteria

Exclusion criteria: 1. Subjects with previous history of hip replacement; 2. Patients who underwent emergency operation again due to postoperative bleeding and other surgical factors; 3. Patients with a history of nervous system diseases, such as stroke, etc; 4. Subjects with visual and auditory impairment and middle ear disease; 5. Subjects with mental or emotional diseases who can not cooperate; 6. Patients with contraindication of butorphanol tartrate; 7. Pregnant or lactating subjects; 8. Patients refuse to participate or are participating in other intervention studies.

Design outcomes

Primary

MeasureTime frame
MMSE score;

Countries

China

Contacts

Public ContactLiu Su

Department of Anesthesiology, Affilicated Hospital of Xuzhou Medical University

150040009@qq.com+86 18118309692

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026