Application of modified vdld induction chemotherapy in acute lymphoblastic leukemia

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000039935

Enrollment

Unknown

Registered

2020-11-14

Start date

2021-01-01

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute lymphocytic leukemia

Interventions

test group:Dex 10mg/m2 d1-4, d9-12, d17-20, d25-28

control group:Dex 10mg/m2 d1-28

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Newly diagnosed adult patients with acute lymphoblastic leukemia; 2. Patients older than 18 years and less than 80 years old; 3. Subjects with ECoG score <= 2.

Exclusion criteria

Exclusion criteria: 1. Subjects with active gastrointestinal bleeding; 2. Patients with other hematological tumor diseases; 3. Patients with serious liver or kidney dysfunction or other severe diseases not suitable for chemotherapy.

Design outcomes

Primary

Measure	Time frame
bone marrow depression;the days of bone marrow depression;infection;chemotherapeutic effect;Dexamethasone concentration;	—

Secondary

Measure	Time frame
gastrointestinal bleeding;blood glucose;osteonecrosis of femoral head;	—

Countries

China

Contacts

Public ContactLuo Xiaohua

The First Affiliated Hospital of Chongqing Medical University

xiaohua-luo@163.com+86 15223058228

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026