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The role of oral losartan in the prevention of acute mountain sickness: a randomized controlled trial

Prophylactic effect of oral Roxadustat to prevent acute altitude illness

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039934
Enrollment
Unknown
Registered
2020-11-14
Start date
2021-06-01
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute altitude illness

Interventions

control group:Oral placebo capsules,the same dosage as Oral Roxadustat
experimental group:oral Roxadustat capsules 50mg, BIW

Sponsors

Western Theater Air Force Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 24 Years

Inclusion criteria

Inclusion criteria: 1. Subjects aged between 18 and 24 years old, including 18 and 24 years old; 2. Those people who rush into the plateau,the sex ratio depends on the specific population at the scene; 3. Subjects without long-term exposure history at high altitude; 4. All subjects must voluntarily participate in and sign a written informed consent form before all assessments.

Exclusion criteria

Exclusion criteria: 1. The subjects with recent history of taking sleeping pills; 2. Subjects who have been engaged in special physical training; 3. Subjects with a history of drug allergy or unable to use drugs for other reasons; 4. Subjects with poor compliance; 5. Patients with cardiovascular disease or other serious diseases; 6. Subjects with recent history of upper respiratory tract infection; 7. Subjects who are smoking; 8. Mental, nervous system diseases and other conditions not suitable for the trial.

Design outcomes

Primary

MeasureTime frame
Lake Louise Score;hemoglobin level;acute altitude illness incidence;

Secondary

MeasureTime frame
oxygen saturation;heart rate;blood pressure;blood lactic acid;

Countries

China

Contacts

Public ContactLiu Yang

Western Theater Air Force Hospital

liuyangjfj@yeah.net+86 18202825736

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026