Knee Osteoarthritis
Conditions
Interventions
A:medial parapatellar (MP) approach
B:minimally invasive of medial parapatellar approach
C:quadriceps-sparing (QS) approach
Sponsors
The Third Hospital of Peking University
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients who underwent total knee arthroplasty for the first time before 2008; 2. Patients aged 50-80 years old, regardless of gender; 3. The patients who voluntarily participate in the clinical trial and sign the informed consent form have good compliance.
Exclusion criteria
Exclusion criteria: 1. Patients with acute trauma, tumor, severe osteoporosis and other immune diseases, severe contracture of muscles around hip / knee joint, etc.; 2. Patients with history of vascular and nerve injury, vasculitis, diabetic foot, etc.; 3. Patients with history of thrombosis in recent 3 months, such as pulmonary embolism, cerebral thrombosis, lower extremity deep venous thrombosis, etc.; 4. Patients with serious primary diseases such as cardio cerebrovascular disease, liver (ALT or ast > 2 times the upper limit of normal value), kidney (BUN > 1.5 times the upper limit of normal value, Cr > 1.5 times the upper limit of normal value), endocrine system, nervous system, hematopoietic system and disturbance of consciousness; 5. Pregnant or lactating patients; 6. Patients allergic to test drugs, human serum albumin allergy or severe allergic constitution, drug or alcohol dependence; 7. Patients who participated in other clinical trials in recent 3 months; 8. Other patients considered unsuitable by clinicians.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| KSS score;knee range of motion;mechanical axis of the lower limb;lateral distal femoral angle;femoral flexion angle;medial proximal tibial angle;tibial slope;lateral patella displacement;lateral patella tilt;VAS Score; | — |
Countries
China
Contacts
Public ContactJiakuo Yu
The Third Hospital of Peking University
Outcome results
None listed