Lung injury
Conditions
Interventions
Group A:Lung driving pressure 10-15cmH20
Group B:Lung driving pressure 15-20cmH20
Sponsors
The First Affiliated Hospital of Shandong First Medical University (Shandong Provincial Qianfoshan Hospital)
Eligibility
Sex/Gender
Female
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. For patients undergoing gynecological laparoscopic surgery under general anesthesia, the operation types include laparoscopic appendectomy, laparoscopic myomectomy and laparoscopic total hysterectomy, and the operation time is 2-4h. 2. BMI: 18-28kg / m2 for patients aged 30-65 years; 3. According to the American Society of anesthesiologists (ASA), the subjects were classified as grade I-II, with good cardiopulmonary function and no other basic medical history; 4. All subjects signed informed consent and cooperated with data collection.
Exclusion criteria
Exclusion criteria: 1. Patients with previous history of pneumonia, atelectasis and pulmonary embolism; 2. Patients with severe cardiopulmonary diseases, such as chronic obstructive pulmonary disease, respiratory and sleep obstructive syndrome, etc.; 3. Patients who have undergone cardiopulmonary surgery, such as lobectomy or cardiopulmonary bypass; 4. The patients with language communication disorder can not cooperate with the postoperative follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| lung compliance;Blood pressure;Heart rate;Arterial blood gas: PaO2 and PaCO2;Extubation time; | — |
Countries
China
Contacts
Public ContactLiu Mengjie
The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital
Outcome results
None listed