Contrast induced acute kidney injury
Conditions
Interventions
Semi-Hydration Group:Hydration rate 0.5 mL/Kg/h
Standard Hydration group:Hydration rate 1 mL/Kg/h
Hydrated Diuretic group:Hydration rate 1 mL/Kg/h + Furosemide 20 mg diuresis immediately after intervention
Sponsors
Department of Cardiology, The Second Hospital of Tianjin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Patients who have indications for coronary intervention and plan to receive coronary angiography or coronary stent implantation; 2. Patients with high risk of ci-aki: Patients with chronic heart failure and chronic kidney disease. Chronic heart failure is defined as: Heart failure with reduced ejection fraction: (1) There were definite symptoms and signs of heart failure; (2) Left ventricular ejection fraction 2 or < 1); Chronic kidney disease is defined as patients with glomerular filtration rate between 15-60 ml / min.
Exclusion criteria
Exclusion criteria: 1. Patients with glomerular filtration rate less than 15 ml / min, or patients requiring long-term hemodialysis or peritoneal dialysis; 2. Patients with acute myocardial infarction who plan to undergo emergency PCI; 3. Patients with acute and chronic infection; 4. Patients with coagulation dysfunction; 5. Patients allergic to furosemide, sulfonamides and thiazides; 6. Uncontrolled grade 3 hypertension or severe hypotension (systolic blood pressure below 90mmHg); 7. Patients with malignant tumor; 8. Pregnancy; 9. Patients with acute diabetic complications such as ketoacidosis or lactic acidosis; 10. Patients with other clinical conditions causing acute renal damage; 11. Patients who were assessed to be intolerant of the intervention and did not sign the informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Contrast induced acute kidney injury; | — |
Secondary
| Measure | Time frame |
|---|---|
| Major adverse cardiovascular events during hospitalization and within 30 days; | — |
Countries
China
Contacts
Public ContactHao Zhang
Department of Cardiology, Second Hospital of Tianjin Medical University
Outcome results
None listed