Auricular fibrillation
Conditions
Interventions
One-stop therapy group:radiofrequency ablation and left atrial appendage closure
warfarin anticoagulant group:warfarin Oral
Levashaban anticoagulant group:Levashaban oral
Postoperative oral warfarin group:oral warfarin after operative
Postoperative oral rivastaben group:oral rivastaben after operative
Postoperative oral dabigatran group:oral dabigatran after operative
Sponsors
Affiliated Hospital of Qingdao University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with paroxysmal, persistent or permanent nonvalvular atrial fibrillation aged 18 or above; 2. Patients with high risk of stroke with cha2ds2 VASC score >= 2.
Exclusion criteria
Exclusion criteria: 1. Patients with warfarin contraindications; 2. Patients with complications other than atrial fibrillation requiring long-term warfarin treatment; 3. Patients with La or LAA thrombosis; 4. Atrial septal aneurysm with patent foramen ovale and right to left shunt; 5. Patients with aortic atherosclerosis and symptomatic carotid artery disease; 6. Patients with valvular diseases with indications for operation; 7. Patients with clinically significant bleeding, stroke or cardiac embolism within 30 days before operation; 8. Patients with ACS within 90 days before operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ischemic events;Bleeding incidents; | — |
Countries
China
Contacts
Public ContactShanglang Cai
Affiliated Hospital of Qingdao University
Outcome results
None listed