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Lidocaine plus low-dose ketamine prevents immediate side effects of three anesthesia-inducing drugs

Lidocaine plus low-dose ketamine prevents immediate side effects of three anesthesia-inducing drugs

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039885
Enrollment
Unknown
Registered
2020-11-13
Start date
2020-11-13
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Children with general anesthesia

Interventions

1:Lidocaine plus esketamine
2:Lidocaine plus saline
3:Esketamine plus saline

Sponsors

Shanghai Children's Medical Centre, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 14 Years

Inclusion criteria

Inclusion criteria: 120 patients undergoing elective surgery for tracheal intubation under general anesthesia, ASA 1-2 grade, age 5-14 years old.

Exclusion criteria

Exclusion criteria: History of drug allergy to propofol, fentanyl, rocuronium, lidocaine, and esketamine, symptoms of nerve palsy, difficulty in catheterization of intravenous trocar, inability to provide informed consent, and difficulty in language communication , Pre-assessment as difficult tracheal intubation, local phlebitis and thrombosis, long-term use of sedatives and analgesics, high blood pressure.

Design outcomes

Primary

MeasureTime frame
Injection pain;Cough;

Countries

China

Contacts

Public ContactChi Wu

Department of Anaesthesiology, Shanghai Children’s Medical Centre, School of Medicine, Shanghai Jiao Tong University, Shanghai, China

frankhardy@163.com+86 13764349625

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026