Study on the characteristics of intestinal microecological community and its correlation with syndromes in patients with early age-related macular degeneration (AMD)

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000039877

Enrollment

Unknown

Registered

2020-11-13

Start date

2020-12-01

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early age-related macular degeneration

Interventions

AMD patients group:Nil

Control group:Nil

Eligibility

Sex/Gender

All

Age

50 Years to 80 Years

Inclusion criteria

Inclusion criteria: AMD patients group 1. In accordance with the diagnostic criteria of early AMD: Beckman initiative for macular research classification committee-Clinical classification of age-related macular degeneration" and "Clinical pathway of age-related macular degeneration in China " 2. Aged 50 to 80 years; 3. Agree to participate in the trial and provide written informed consent. Control group 1. Aged 50 to 80 years; 2. Those without AMD-related pathological changes, glaucoma, uveitis or other fundus diseases, which involves the macular area and retinal vessels; 3. Those without diabetes, hypertension, malignant tumors, mental diseases, immune system diseases and other diseases, all indicators of physical examination are within the normal range; 4. Those without infectious diseases or antibiotics taken in the past 4 weeks; 5. Those without any intestinal related diseases including acute gastroenteritis in the past 4 weeks; 6. Those without having taken probiotics/prebiotics or other micro-ecological regulators, Chinese medicines (including Chinese patent medicine, decoctions with clear ingredients, or remedies with unknown ingredients) in the past 4 weeks, or overeating foods with antibacterial effects (such as chili,ginger,garlic,etc.); 7. Agree to participate in the trial and provide written informed consent.

Exclusion criteria

Exclusion criteria: AMD patients group 1. Those with diabetes,hypertension,malignant tumors,mental diseases,immune system diseases and other diseases; 2. Those with glaucoma,uveitis or other fundus diseases,which involves the macular area and retinal vessels; 3. Those with infectious diseases or antibiotics taken in the past 4 weeks; 4. Those with any intestinal related diseases including acute gastroenteritis in the past 4 weeks; 5. Those with having taken probiotics/prebiotics or other micro-ecological regulators, Chinese medicines (including Chinese patent medicine, decoctions with clear ingredients,or remedies with unknown ingredients) in the past 4 weeks,or overeating foods with antibacterial effects (such as chili, ginger,garlic,etc.); 6. Those with other stages of AMD.

Countries

China

Contacts

Public ContactLina Liang

Eye Hospital, China Academy of Chinese Medical Sciences

lianglina163@163.com+86 010-68683451

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026