Chronic atrophic gastritis
Conditions
Interventions
Sponsors
Affiliated Hospital of Shaanxi University of traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) The outpatients and inpatients with atrophic gastritis, mild, moderate and severe intestinal metaplasia or mild to moderate dysplasia were diagnosed by gastroscopy and histopathology; (2) Those who meet the diagnostic criteria of TCM syndromes; (3) The age ranged from 18 to 70 years old; (4) The subjects were informed and voluntarily signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Severe dysplasia was diagnosed by histopathology; (2) Patients with history of peptic ulcer, gastric polyp and gastric surgery; (3) Long term use of NSAID drugs; (4) Patients suspected of gastric cancer or other systemic malignant lesions; (5) Patients with heart, cerebrovascular, liver, kidney, hematopoietic system and other primary diseases (ALT > 80 U / L, and / or ast > 80 U / L, renal dysfunction); (6) Mental illness, mental retardation and language disorder; (7) Patients with history of epilepsy and other central neuropathy; (8) Pregnant or preparing for pregnancy and lactation; (9) Allergic constitution and allergic history to the test drug or control drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Histopathological score of gastric mucosa;Pepsinogen determination;Determination of gastrin;Incidence of gastric cancer; | — |
Secondary
| Measure | Time frame |
|---|---|
| Symptom scores;Endoscopic mucosal lesion score;Based on the score of the patient reported clinical outcome scale (pro scale); | — |
Countries
China
Contacts
Public ContactLiu Li
Shaanxi University of Traditional Chinese Medicine,
Outcome results
None listed