knee osteoarthritis
Conditions
Interventions
Case series:PRP injection
Sponsors
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
38 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Adults aged 38 and 85 years; 2. Confirmed clinical diagnosis of unilateral or bilateral KOA in accordance with the 2010 Clinical Diagnostic Criteria for the Diagnosis and Treatment of Osteoarthritis by the Chinese Medical Association Rheumatology Branch. Specifically, the diagnosis is confirmed by meeting items 1+2+3+4, items 1+2+5 or items 1+4+5 (item 1: knee pain most of the time in the past month; item 2: crepitus; item 3: morning stiffness lasting = 38 years; and item 5: palpable bony enlargement); 3. Report average knee pain over the past week >= 20 on a 100 mm visual analogue scale; 4. No history of musculoskeletal pathology or trauma in the past 6 months.
Exclusion criteria
Exclusion criteria: (1) Acute, infectious diseases or other systemic diseases; (2) Knee function affected by another disease of the nervous or musculoskeletal system, such as stroke, fractures and rheumatoid arthritis; (3) hemoglobin concentration is lower than 12 g/dL or platelet counts is lower than 150,000 /uL; (4) anticoagulant or antiplatelet drugs were taken within 10 days before injection; (5) hormone was taken within 2 weeks before injection; (6) not suitable for X-rays test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC scores;Gender;Ages;BMI;Kellgren-Lawrence (K-L) level;VAS;Injection details;HWAS; | — |
Countries
China
Contacts
Public ContactWu Shaoling
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
Outcome results
None listed