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Effect of three different ventilation modes on postoperative pulmonary complications in adult patients undergoing cardiac surgery

Effect of three different ventilation modes on postoperative pulmonary complications in adult patients undergoing cardiac surgery: a prospective, randomized, controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039840
Enrollment
Unknown
Registered
2020-11-12
Start date
2020-11-10
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pulmonary complications

Interventions

PCV-VG:Pressure Controlled Ventilation-volume Guarantee
PCV:pressure controlled ventilation
VCV:volume controlled ventilation

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged >= 18 years; 2. Selective cardiac surgery will be performed in the median sternal incision under the extracorporeal circulation; 3. Signed informed consent.

Exclusion criteria

Exclusion criteria: 1. The aortic arch and other deep hypothermic stopping operations; 2. Heart transplantation, pulmonary arterial thrombosis; 3. Self-reported pregnancy; 4. Preoperative long-term use of hormone systemic therapy >= 3 months; 5. Already joined other similar research in recent 3 months; 6. preoperative mechanical ventilation within 60 days of surgery, use of a double-lumen endotracheal tube or one-lung ventilation; 7. Neuromuscular dysfunction; 8. Preoperative extracorporeal membrane oxygenation support or ventricular assist device.

Design outcomes

Primary

MeasureTime frame
Incidence of pulmonary complications 7 days after surgery;

Secondary

MeasureTime frame
the severity grade of postoperative pulmonary complications;Postoperative extubation time;Length of ICU stay;Length of hospital stay;All-cause mortality in 30 days after surgery;

Countries

China

Contacts

Public ContactHai Yu

West China Hospital, Sichuan University

yuhaishan117@hotmail.com+86 18980601548

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026