cervical cancer
Conditions
Interventions
SBRT group:SBRT technique assisted by cervical fixator
Sponsors
Wuhan University Renmin Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Patients with locally advanced cervical cancer in stage IB2 -IVA (2018 FIGO staging); 2) ECOG 0-1 level; life expectancy> 6 months; 3) 18-70 years old; 4) No chemotherapy was used before selection; 5) Complete standard pelvic external radiation therapy; 6) No surgical treatment; 7) No serious allergy history; 8) Hemoglobin >= 100 g/L, WBC >= 3.5 x 10^9/L, neutrophils >= 1.5 x 10^9/L, platelets >= 100 x 10^9/L; CR <= 1.5 times the upper limit of normal, TB <= 2.5 times the upper limit of normal, AST and ALT <= 2.5 times the upper limit of normal, AKP <= 2.5 times the upper limit of normal; 9) Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Those who cannot be followed up; 2) There are distant metastases such as visceral metastasis; 3) Those who have serious medical or psychiatric diseases that cannot be treated as prescribed by the doctor; 4) Severe infections are in active stage or under clinical control; 5) The external radiation does not reach the minimum therapeutic dose.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ORR;Recent adverse reactions; | — |
Secondary
| Measure | Time frame |
|---|---|
| DCR;PFS;OS;Long-term toxic and side effects; | — |
Countries
China
Contacts
Public ContactXiming Xu
Wuhan University Renmin Hospital
Outcome results
None listed