general anesthesia
Conditions
Interventions
Protective Group:PEEP combined with recruitment maneuver
Conventional Group:Conventional ventilation
Sponsors
Hospital of Chengdu office of People's Government of Tibetan Autonomous Region
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Selective general anesthesia with expected operation time >= 1h; 2. Tibetan patients living in Tibetan Plateau more than three generations, entering the plain = 18 years; 4. American Society of Anesthesiologists (ASA) II-III.
Exclusion criteria
Exclusion criteria: 1. Those who are participating in other clinical trials or do not agree to participate the clinical trials; 2. Surgery requiring single lung ventilation, prone position and lateral position; 3. General anesthesia surgery within 30 days, and invasive and / or non-invasive mechanical ventilation time >= 30min within 30 days; 4. History of lung surgery; 5. History of severe lung diseases, including severe obstructive pulmonary disease (chronic obstructive pulmonary disease) COPD), acute exacerbation of COPD, lung infections, bronchial asthma, bronchiectasis, etc .; 6. History of thoracic or intrathoracic diseases, including thoracic deformities, mediastinal tumors, chest tumors, etc .; 7. Hemodynamic instability (mean arterial pressure MAP <= 60mmHg cannot be corrected by fluid replacement and vasoactive drugs), refractory shock, acute coronary syndrome, New York Heart Association Heart Function ,NYHA) III- IV; 8. Female during pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pulmonary complications ; | — |
Countries
China
Contacts
Public ContactShang Kaixi
Hospital of Chengdu Office of People's Government of Tibetan Autonomous Region
Outcome results
None listed