Primary Sjogren syndrome
Conditions
Interventions
PSS patient group:No intervention
Healthy control group:No interwention
Sponsors
Department of Stomatology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The subjects should meet the following criteria: pSS patient group: 1. Signed informed consent form with date 2. Commitment to abide by the research procedures, and cooperate with the implementation of the whole process of research 3. Men and women are not limited, age is not limited to 4. All the pSS patients enrolled in this study met the American Rheumatic Association ((ACR))-European Alliance against Rheumatism ((EULAR)) criteria. Non-pSS:1. was excluded from drug use, diabetes, hypertension, infection and other diseases. Signed informed consent form with date 2. Commitment to abide by the research procedures, and cooperate with the implementation of the whole process of research 3. Men and women are not limited, age is not limited to 4. The age matched that of the experimental group. The patients in this group were composed of patients who underwent minor lip surgery and lip trauma treatment, and then pSS was excluded by pathological examination.
Exclusion criteria
Exclusion criteria: Subjects who meet any of the following criteria will be excluded from this study: 1. Specific disallowed drugs are currently being used. 2. Be in pregnancy or lactation period 3. There are febrile diseases in a specific period of time. 4. Treatment with other experimental drugs within a specific period of time. 5. With specified diseases or conditions excluded from the study (physical or psychological, physical findings).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| biomark;antinuclear antibodies;anti-SSA antibody;anti-SSB antibody;rheumatoid factors;Erythrocyte sedimentation rate;C reactive protein;immunoglobulin G;immunoglobulin A;immunoglobulin M;complement 3;complement 4; | — |
Countries
China
Contacts
Public ContactGao Yiming
Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Outcome results
None listed