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Early biological endophenotype and genetic mechanism of ASDs' high-risk infants

Early biological endophenotype and genetic mechanism of ASDs' high-risk infants

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000039818
Enrollment
Unknown
Registered
2020-11-10
Start date
2020-11-15
Completion date
Unknown
Last updated
2021-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism spectrum disorder

Interventions

Sponsors

The Third Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 2 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria of the test group: aged 9 months to 24 monthsthe subjects had at least one older sibling who met the ASD diagnostic criteria of the American Diagnostic Diagnostic Statistics Manual, Fifth Edition (DSM-V); the first language was Mandarin; Parents volunteer to cooperate with the assessment and follow-up, and have the ability to fill out the questionnaire independently;no special eating habits. The inclusion criteria of the control group: aged 9 months to 24 months; no older siblings met the ASD diagnostic criteria of the American Psychiatric Diagnostic Statistical Manual, Fifth Edition (DSM-V); the first language was Mandarin; parents volunteered Evaluation and follow-up, the ability to fill out the questionnaire independently;no special eating habits. The inclusion criteria of the verification group: aged 24 months; Being diagnosed by an specialist of our center and meeting the diagnostic criteria of Autism Spectrum Disorder (ASD) in the Fourth Edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V); the first language was Mandarin; parents volunteered Evaluation and follow-up, the ability to fill out the questionnaire independently;no special eating habits.

Exclusion criteria

Exclusion criteria: Exclude other physical diseases such as epilepsy, delirium, hearing impairment, visual impairment, etc.; exclude Down syndrome, Rett syndrome, Williams syndrome, fragile X syndrome, special language development disorders and so on; metabolic disease, digestive system disease, liver and kidney damage or other chronic organic diseases.

Design outcomes

Primary

MeasureTime frame
biological endophenotype;gene;

Countries

China

Contacts

Public ContactDeng Hongzhu

The Third Affiliated Hospital of Sun Yat-Sen University

denghzh@mail.sysu.edu.cn+86 13829731094

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026