Breast cancer
Conditions
Interventions
Gold Standard:axillary lymph node dissection
Index test:triple-tracer 
lymph 
biopsy
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Female, age at diagnosis >= 18; 2. Pathologically diagnosed invasive breast cancer, and pathologically or clinically diagnosed ipsilateral axillary lymph node metastasis; 3. Neoadjuvant chemotherapy performed according to pertinent guidelines, and preoperative X-ray, breast ultrasound, breast MRI and physical examination after neoadjuvant therapy all suggest node-negative diseases; 4. No other concomitant malignancies; 5. Normal bone marrow function, neutrophil >= 2.5 x 10^9/L, hemoglobin >= 100g /L, platelets >= 100 x 10^9/L, normal coagulation function; 6. Normal liver and kidney function; 7. Normal ECG, left ventricular ejection fraction (LVEF) >= 55%; 8. ECOG score 0-1 points.
Exclusion criteria
Exclusion criteria: 1. Distant metastasis; 2. History of axillary surgery; 3. History of charcoal allergy; 4. Pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Laboratory examination (blood routine, urine routine, blood biochemistry);Physical examination;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactChen Jie
West China Hospital, Sichuan University
Outcome results
None listed