Head and neck malignances
Conditions
Interventions
group according to different treatment schemes:Nil
Sponsors
The First Medical Center of Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients are grouped by anatomic site and pathological types of the primary tumor(eg.Squamous cell carcinoma of the nasal cavity and sinuses, olfactory neuroblastoma, squamous cell carcinoma of the nasopharynx,oropharynx,hypopharynx and glottic larynx and so on); 2. Definitive pathological diagnosis locally advanced head and neck cancer; 3. KPS >= 70 or ECOC 0-1; 4. Patients are 18 to 70 years old; 5. Patients are supposed to survive over 2 years at least; 6. Imaging(MRI or enhanced MRI,or US)as a aid to identify the invision of surrounding tissue and lymph node metastesis; 7. The cervical and supraclavicular regional lymph node metastasis are allowed; 8. Patients are required to have normal hepatic, renal, and bone marrow function, without severe hematologic toxicity and severe complications. Surgery, induction chemotherapy, concurrent chemoradiotherapy, consolidation chemotherapy, targeted therapy and immunotherapy were allowed in the study; 9. Patients voluntarily participate in the study and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients have underwent palliative or incomplete tumor resection. 2. Patients who have poor hepatic and renal function, severe hematologic toxicity and complications can not tolerate surgery, induction chemotherapy, concurrent chemotherapy, consolidation chemotherapy, target therapy and immunotherapy and so on. 3. The area planed to be received radiotherapy had a history of irradiation. 4. Pregnant females.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| acute side effects;late side effects;curative effect; | — |
Countries
China
Contacts
Public ContactLin Ma
Department of Radiation Oncology, the First Medical Center of Chinese PLA General Hospital
Outcome results
None listed