Correlation of SIRT6 with glycolipid metabolism and urinary protein in patients with type 2 diabetes mellitus

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000039808

Enrollment

Unknown

Registered

2020-11-10

Start date

2020-12-01

Completion date

Unknown

Last updated

2022-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetes mellitus

Interventions

Normal UACR group:None

Pre DM group:None

Normal group:None

Micro UACR group:None

UACR group:None

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed T2DM. 2. Patient with pre-diabetes. 3. Healthy people.

Exclusion criteria

Exclusion criteria: 1.In the last 3 months acute diabetic complications, such as diabetic hyperosmotic coma ,diabetic ketoacidosis, etc; 2.With recent stress conditions, such as infection, surgery, trauma,etc or special physical conditions, such as pregnancy and lactation; Or aged < 18 years. 3. Patients were treated by ACEI, ARB or SGLT-2i. 4. Severe liver function, damageIntentional cerebrovascular disease, infectious disease and history of malignant tumor or anamnesis of nephropathy.

Design outcomes

Primary

Measure	Time frame
SIRT6;	—

Secondary

Measure	Time frame
UACR;FPG;2h-PG;FINS;HbA1c;UA;UC;HDL-C;LDL-C;TC;TG;BUN;Cr;HOMA-IR;Insulin sensitivity index;eGFR;TNFa;HIF1a;	—

Countries

China

Contacts

Public ContactChe Bian

The Fourth Affiliated Hospital of China Medical University

bianche1028@163.com+86 18900912240

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 22, 2026