acute type A aortic dissection
Conditions
Interventions
Traditional surgery group vs New technology group:Simple axillary artery intubation vs. Intraoperative stent occlusion combined with axillary artery and femoral artery intubation for sun's operation
Sponsors
Beijing Anzhen Hospital of Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. According to the guidelines for diagnosis and treatment of thoracic aortic disease issued by ACC / AHA in 2010, the clinical and clinical data were analyzed Acute type A aortic dissection was diagnosed by imaging and the onset was within two weeks; 2. The age ranged from 18 to 70 years; 3. If the patient had a previous laboratory test on admission, the glomerular filtration rate (GFR) decreased by 35% or SCr 3 mg / dl (26. 5 mmol / L) in comparison with the two test values; the glomerular filtration rate (GFR) was less than 60 ml / min / 1.73 m2, or the serum creatinine value (SCR) was higher than normal 5 times of the normal upper limit, and the urine volume of 6-12 hours was less than 0.5 ml / kg / hr; 4. Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) was more than twice the normal high limit; 5. The lactic acid value was more than 3 mmol / L; 6. The amylase value was 3 times higher than the normal upper limit; 7. Signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Previous chronic liver and kidney insufficiency; 2. Gastrointestinal dysfunction caused by other reasons, such as intestinal obstruction and digestive tract 3. Previous history of severe cerebral infarction (with sequelae); 4. Preoperative endotracheal intubation status; 5. Takayasu arteritis Results: Patients with inflammatory aortic diseases such as Behcet's disease; 6. Previous cardiac and vascular surgery; 7. Patients with a history of malignant tumor or who had received chemotherapy and radiotherapy; 8. Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 30 day hospital mortality;Cardiopulmonary bypass time;Mechanical ventilation time of ventilator;Incidence of acute kidney injury;Incidence of liver failure;Incidence of stroke;Detention time in intensive care unit;Blood transfusion volume;Incidence of paraplegia or paraplegia;Operation time;Hospitalization expenses; | — |
Countries
China
Contacts
Public ContactJun-Ming Zhu
Beijing Anzhen Hospital of Capital Medical University
Outcome results
None listed