Breast Cancer
Conditions
Interventions
36.5Gy/10F group:hypofractionated radiotherapy (10F)
42.5Gy/16F group:hypofractionated radiotherapy (16F)
Sponsors
The First Medical Center of Chinese PLA General Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged from 18 to 75 years old; 2. Female; 3. Patients conventionally recieve adjuvant chemotherapy after conservative surgery(neo-chemotherapy is permitted); 4. Histopathology examination shows invasive carcinoma; 5. TNM stging :pT1-2 pN0-1 M0; 6. KPS >= 70 or ECOC 0-1; 7. Patients are supposed to survive over 5 years at least; 8. Simultaneous endocrine therapy and targeted therapy for HER-2 are permitted; 9. Patients voluntarily participate in study and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Controlateral breast cancer as well as DCIS are not allowed, no matter when diagnosed; 2. Systematic metastasis exist; 3. The regional area planed to be received radiotherapy had a history of irradiation; 4. Patients failed to completed adjuvant chemotherapy and/or targeted therapy as schedule; 5. Active connective tissue disease involved in the treatment area; 6. Patients with severe complications,such as hypertension, coronary heart disease,mental disease or patients who have a history of severe allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| acute side effects;late side effects; | — |
Secondary
| Measure | Time frame |
|---|---|
| outcomes; | — |
Countries
China
Contacts
Public ContactLin Ma
Department of Radiation Oncology, First Medical Center of Chinese PLA General Hospital
Outcome results
None listed