early-onset sepsis in newborns
Conditions
Interventions
Gold Standard:According to the expert consensus on the diagnosis and treatment of neonatal sepsis (2019 edition), neonatal early infection refers to the infection occurring within 72 hours after birth
Index test:PCT, CRP, NLR
Sponsors
Yiwu Maternity and Children Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Newborns who delivered in our hospital from December 2020 to December 2021, whose mothers have no major internal or surgical diseases and have high risk factors for infection. Risk factors of infection refer to those who meet any of the following conditions: (1) Premature rupture of membranes with > for 18h; (2) Maternal fever in the third trimester of pregnancy or increased blood PCT, CRP and WBC; (3) The amniotic fluid III pollution or odor; (4) Chorioamnionitis; (5) Positive vaginal GBS culture at 34 weeks of pregnancy; (6) History of fetal distress or neonatal asphyxia; (7) Placental abruption; (8) Gestational age less than 33 weeks.
Exclusion criteria
Exclusion criteria: Severe congenital malformation, genetic metabolic diseases, chromosomal diseases, and failure to complete the study procedures for various reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| early-onset sepsis;blood culture;blood routine;Clinical symptoms of infection;SEN, SPE, ACC, AUC of ROC, PPV, NPV; | — |
Countries
China
Contacts
Public ContactShujun Chen
Yiwu Maternity and Children Hospital
Outcome results
None listed