Efficacy and safety of high cut-off filter - continuous renal replacement therapy in sepsis - induced acute renal injury

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000039725

Enrollment

Unknown

Registered

2020-11-06

Start date

2021-01-01

Completion date

Unknown

Last updated

2021-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis - induced acute renal injury

Interventions

High cut-off Group:High - cut filter was used for dialysis treatment

AV600s Group:AV600s filter used for dialysis treatment

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients in need of CRRT(AKI, ESRD, Acute poisoning, et.al, who have reached the intervention standard of renal replacement); hemodynamic stability who can tolerate RCA-CVVHDF treatment mode; Current use of temporal CVCs; Aged 18 -70 years old; Informed consent.

Exclusion criteria

Exclusion criteria: Low blood pressure, systolic blood pressure below 90mmHg;Had congestive heart failure (ejection fraction <= 50%), acute myocardial infarction or stroke in the last 6 months; Other clinicians think that the overall condition is serious or inappropriate to participate in the study.

Design outcomes

Primary

Measure	Time frame
IL-6;TNF-a;	—

Countries

China

Contacts

Public ContactZhao Yuliang

Sichuan University West China Hospital

309444318@qq.com+86 13880801130

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026