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The effects of time of day on pain after cesarean section and its possible mechanism

The effects of time of day on pain after cesarean section and its possible mechanism

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000039720
Enrollment
Unknown
Registered
2020-11-06
Start date
2020-11-09
Completion date
Unknown
Last updated
2021-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean delivery

Interventions

Morning group:PCIA
Afternoon group:PCIA

Sponsors

The Second Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Subjects aged 20 to 40 years; 2. Subjects with ASA scores I-II; 3. Singleton term pregnancy; 4. Patients who voluntarily signed informed consent for cesarean section and postoperative patient-controlled analgesia; 5. The subjects who are willing to participate in the study and sign the informed consent; 6. In morning group, the operation started within 6:00-12:00, and the estimated end time was before 12:00; in afternoon group, the operation started within 12:00, and the estimated end time was before 18:00.

Exclusion criteria

Exclusion criteria: 1. Subjects with acute and chronic pain such as long-term low back pain and neuropathic pain; 2. Subjects taking anti-inflammatory drugs, opioids or related diseases for a long time; 3. Subjects allergic to opioids and tramadol; 4. Subjects who cannot cooperate with the study for any reason.

Design outcomes

Primary

MeasureTime frame
VAS;

Secondary

MeasureTime frame
the PCA compressions after operation;the dose of PCA;Experimental pain thresholds;endorphin;enkephalin;dynorphin;IL;TNF-a;

Countries

China

Contacts

Public ContactHe Huang

Department of Anesthesiology, the Second Affiliated Hospital of Chongqing Medical University

coolduangy3344@126.com+86 13708385559

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026