Cesarean delivery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Subjects aged 20 to 40 years; 2. Subjects with ASA scores I-II; 3. Singleton term pregnancy; 4. Patients who voluntarily signed informed consent for cesarean section and postoperative patient-controlled analgesia; 5. The subjects who are willing to participate in the study and sign the informed consent; 6. In morning group, the operation started within 6:00-12:00, and the estimated end time was before 12:00; in afternoon group, the operation started within 12:00, and the estimated end time was before 18:00.
Exclusion criteria
Exclusion criteria: 1. Subjects with acute and chronic pain such as long-term low back pain and neuropathic pain; 2. Subjects taking anti-inflammatory drugs, opioids or related diseases for a long time; 3. Subjects allergic to opioids and tramadol; 4. Subjects who cannot cooperate with the study for any reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| the PCA compressions after operation;the dose of PCA;Experimental pain thresholds;endorphin;enkephalin;dynorphin;IL;TNF-a; | — |
Countries
China
Contacts
Department of Anesthesiology, the Second Affiliated Hospital of Chongqing Medical University