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Evaluation of Posterior Fossa Decompression (PFD) without or with Cerebellar Tonsil Thermocoagulation (PFDCT) for Arnold-Chiari Malformation Type I with Syringomyelia: a ramdomised controlled trial

Evaluation of Posterior Fossa Decompression (PFD) without or with Cerebellar Tonsil Thermocoagulation (PFDCT) for Arnold-Chiari Malformation Type I with Syringomyelia: a ramdomised controlled trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039678
Enrollment
Unknown
Registered
2020-11-05
Start date
2021-02-01
Completion date
Unknown
Last updated
2021-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arnold-Chiari Malformation Type I with Syringomyelia

Interventions

A Group:Posterior Fossa Decompression
B Group:Posterior Fossa Decompression (PFD) with Cerebellar tonsil Thermocoagulation (PFDCT)

Sponsors

Fujian Medical University Union Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Age: 18-65 years old; (2) There are clinical symptoms related to Chiari malformation type I combined with syringomyelia; (3) Sagittal MRI showed that the lower edge of the cerebellar tonsil was 5 mm below the foramen magnum (McRac line), and MR of the cervical thoracic spine showed syringomyelia. (4) No history of trauma in the craniocervical junction.

Exclusion criteria

Exclusion criteria: (1) Combined with spinal trauma, nervous system infectious diseases, spinal cord tumors, tethered cord syndrome, posterior fossa decompression or spinal cord disease surgery, etc.; (2) Patients with invaded skull base, flat skull base, scoliosis, atlantoaxial dislocation, severe ventral compression of the brainstem and spinal cord at the craniocervical junction; (3) There are other intracranial lesions.

Design outcomes

Primary

MeasureTime frame
Karnofsky Performance Scale;Chicago Chiari Outcome Scale;MRI of the craniocervical junction;

Secondary

MeasureTime frame
Visual Analogue Scale;Improvement in the Syringomyelia;Complications;

Countries

China

Contacts

Public ContactChen Chunmei

Fujian Medical University Union Hospital

cmchen2009@sina.com+86 13509339040

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026