Liver cirrhosis
Conditions
Interventions
Healthy control:None
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18 to 75 years; 2) Diagnosed with liver cirrhosis; 3) Receive elective TIPS.
Exclusion criteria
Exclusion criteria: 1) Previous treatments with TIPS or surgical shunt; 2) Presence of portal vein thrombosis before enrollment; 3) Consumption of anticoagulant or antiplatelet medications; 4) Thrombophilia; 5) Prescribed with medical enternal or parenternal nutrition, antibiotics, or lactulose within 4 weeks before enrollment; 6) Gastrointestinal bleeding, spontaneous bacterial peritonitis, hepatorenal syndrome, or hepatopulmonary syndrome is uncontrolled or stable less than 1 week; 7) Vital organ insufficiency (heart, lung, kidney, brain, etc.); 8) Residency in high altitudes (higher than 2500 meters above the sea level); 9) In pregnancy or lactation; 10) Child-Pugh score exceeds 12 points or aminotransferase elevation exceeds five times of upper limits of normal; 11) Cholestatic diseases (primary biliary cirrhosis, primary sclerosing cholangitis, extrahepatic bile duct obstruction etc.); 12) Presence of malignancy; 13) Portal cavernoma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiota;PVT; | — |
Countries
China
Contacts
Public ContactHao Wu
West China Hospital, Sichuan University
Outcome results
None listed