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Effect of temperature protection on postoperative immune function in elderly patients with colorectal cancer

Effect of temperature protection on postoperative immune function in elderly patients with colorectal cancer

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000039659
Enrollment
Unknown
Registered
2020-11-04
Start date
2020-11-10
Completion date
Unknown
Last updated
2021-02-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer

Interventions

Body temperature Protection group (T group):Intraoperative routine temperature protection+Inflatable heating system
Control group (C Group):Intraoperative routine temperature protection

Sponsors

Affiliated Hospital of Traditional Chinese Medicine, Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged >= 65 years; 2. A clear diagnosis of colorectal cancer and the need for radical resection of colorectal cancer; 3. No radiotherapy or chemotherapy; 4. No severe diarrhea, liver and kidney failure or cardiopulmonary insufficiency; 5. American Society of Anesthesiologists (ASA) Level I-III; 6. Body mass index (BMI) is between 18.5 and 30; 7. Abdominal CT examination showed no obvious lymph node or distant metastasis.

Exclusion criteria

Exclusion criteria: 1. History of abdominal surgery; 2. Endocrine or immune system dysfunction; 3. Recent blood transfusion; 4. Poor patient compliance or operation time >6 h.

Design outcomes

Primary

MeasureTime frame
interleukin 17 (IL17);transforming growth factor-ß (TGF-ß);Interleukin- 6 (IL-6);Intraoperative core body temperature;Incidence of postoperative complications;Lymphocyte count;

Secondary

MeasureTime frame
Vital signs;Postoperative hospital stay;White blood cells;

Countries

China

Contacts

Public ContactYing Zhang

Department of Anesthesiology, Affiliated Hospital of Traditional Chinese Medicine, Southwest Medical University

zhangying021210@163.com+86 13551720908

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026