Effects of sevoflurane inhalation anesthesia on proliferation and apoptosis of colon cancer cells in vitro: a randomized controlled trial.

The role of PI3K/Akt in the effect of sevoflurane on colorectal cancer microenvironment

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000039651

Enrollment

Unknown

Registered

2020-11-04

Start date

2020-11-01

Completion date

Unknown

Last updated

2021-02-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Sevo:Sevoflurane inhalation anesthesia was performed during the operation

Pro:propofol intravenous anesthesia was performed during the operation

Sevo+Pro:sevoflurane—propofol combined anesthesia during the operation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients scheduled for laparoscopic radical resection of colon cancer under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Patients receiving preoperative chemoradiotherapy; 2. Patients with history of allergy to narcotic drugs; 3. Patients with infectious diseases before operation; 4. Patients with other malignant tumors.

Design outcomes

Primary

Measure	Time frame
Postoperative mortality;	—

Countries

China

Contacts

Public ContactZhu Zhaoqiong

Affiliated Hospital of Zunyi Medical University

ganzhu_zq@sina.com+86 13035529980

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026