Maintenance of sinus rhythm after radiofrequency ablation therapy for atrial fibrillation concomitant with valve replacement surgery
Conditions
Interventions
control group:amiodarone hydrochloride
Sponsors
Department of Cardiovascular Surgery, Shandong Provincial Hospital affiliated to Shandong First Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Those who are 18 or younger; 2. Those with 45 kg <= body weight <= 100 kg; 3. Those subjects with 3 hours <= new onset AF / AF time <= 48 hours after cardiovascular surgery.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindication of anticoagulation; 2. The objects of taboo of law conversion; 3. Subjects with hemodynamic instability; 4. Subjects of acute coronary syndrome; 5. Patients with QRS greater than 0.14 seconds or ventricular rate less than 50 beats / min without pacemaker; 6. Patients who have used class I or class III antiarrhythmic drugs within 24 hours; 7. Patients with QTc interval greater than 0.480s in females and 0.470s in males; 8. Patients with NYHA cardiac function grade IV; 9. Patients with diastolic blood pressure lower than 60mmhg or systolic blood pressure lower than 95mmhg; 10. Subjects with blood potassium < 3.5mmol/l; 11. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| maintenance of sinus rhythm after radiofrequency ablation therapy for atrial fibrillation concomitant with valve replacement surgery; | — |
Countries
China
Contacts
Public ContactHaizhou Zhang
Department of cardiovascular surgery, provincial hospital affiliated to Shandong First Medical University
Outcome results
None listed