Knee replacement
Conditions
Sponsors
The First Affiliated Hospital of University of science and technology of China (Anhui Provincial Hospital)
Eligibility
Sex/Gender
All
Age
66 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. 160 patients scheduled for total knee arthroplasty; 2. Patients aged 40-65 years, regardless of gender, Asai or II; 3. Patients with normal pulmonary function before operation did not receive radiotherapy, chemotherapy and immunosuppressive therapy; 4. Patients with the same surgical procedure by the same group of doctors; 5. Patients who voluntarily participate and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with severe liver and kidney dysfunction, coagulation dysfunction and allogeneic blood transfusion during perioperative period; 2. Patients with autoimmune diseases or low immune function; 3. Patients with known gastrointestinal bleeding and cardiovascular adverse reactions to NSAIDs; 4. Patients with hypertension and severe heart failure; 5. Patients using enoxacin, lomefloxacin and norfloxacin; 6. Other patients considered unsuitable by researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| troponin;myoglobin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change value of hemodynamics;The change value of Lactic; Inflammatory cytokines; | — |
Countries
China
Contacts
Public ContactShu Shuhua
The First Affiliated Hospital of University of science and technology of China (Anhui Provincial Hospital)
Outcome results
None listed